Hereditary deafness in the white cat

by I. W. S. Mair

Publisher: [s.n.], Publisher: distributed by the Almqvist & Wiksell Periodical Company in Uppsala, Stockholm

Written in English
Published: Pages: 48 Downloads: 82
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  • Deafness -- Genetic aspects.,
  • Pigmentation disorders -- Genetic aspects.,
  • Labyrinth (Ear) -- Diseases.,
  • Cats -- Diseases

Edition Notes

Statementby I. W. S. Mair.
SeriesActa oto-laryngologica : Supplement ; 314
LC ClassificationsRF292 .M34
The Physical Object
Pagination48 p. :
Number of Pages48
ID Numbers
Open LibraryOL4595866M
LC Control Number77358381

Background:Congenital sensorineural deafness (CSD) occurs in Border Collies, but its prevalence and inheritance are unknown. This study estimated the prevalence of CSD in Border Collies and investigated its association with phenotypic attributes linked to the Australian Cattle Dog (n=) 15% English Cocker Spaniel (n=1,) 7 AKC/CHF: Murphy, Strain 'Genetics of Hereditary Deafness in the Domestic Dog' candidate genes – A free PowerPoint PPT presentation (displayed as a Flash slide show) on - id: ZDc4N   This topic is actually news to me too. I didn’t know hereditary deafness was a major concern in white cats with blue eyes until one of my Facebook followers mentioned something to me. Per the Cornell Feline Heath Center, “researchers found that only 17 to 22 percent of white cats with non-blue eyes are born deaf. The percentage rises to 40 Congenital hereditary deafness in most dog breeds is associated with 1 of 2 classical pigmentation genes responsible for white or light skin and fur coloration: piebald and merle. 1 The pigment locus S has 3 recessive alleles: Irish spotting, piebald, and extreme piebald; dogs with the dominant allele have solid color. Dogs homozygous for 1 of the recessive alleles have white ://

Canine congenital sensorineural deafness (CCSD) affects predisposed breeds of dogs and is primarily caused by an atrophy of the stria vascularis of the organ of Corti. The analysis of the brainstem auditory evoked response (BAER) is a reliable method for the evaluation of hearing in animals as it allows an accurate detection of unilateral or Congenital Sensorineural Deafness in Australian Stumpy-Tail Cattle Dogs Is an Autosomal Recessive Trait That Maps to CFA10 By Susan Sommerlad, Allan F. McRae, Brenda McDonald, Isobel Johnstone, Leigh Cuttell, Jennifer M. Seddon and Caroline A. O'Leary

Hereditary deafness in the white cat by I. W. S. Mair Download PDF EPUB FB2

Results showed no evident relationship between the age of the white cat and the appearance, severity or completeness of hearing loss. A large variety of hearing remnants was encountered in partly deaf animals which is tentatively related to a similar variety of histological damage of the cochlea described in a companion paper (Rebillard M Hereditary deafness in the white cat.

Uppsala: [s.n.] ; Stockholm: distributed by the Almqvist & Wiksell Periodical Co., (OCoLC) Document Type: Book: All Authors / Contributors: I W S Mair   INTRODUCTION Hereditary deafness, associated with pigmentation disorders, has been reported in mink [8,17], dog [1,9,11] and man [18].

This kind of abnormality was originally described in white cat by Sichel [15]. Since then, numerous studies have been devoted to deaf white cats (see [2]). What is the risk of deafness in a white cat. The risk of deafness in relation to coat colour and eye colour is shown in the figure below.

If deafness occurs, it may be either unilateral or bilateral. Overall, deaf cats with white coat colour and one or both blue eyes, make up around about % of the total cat 2 days ago  Hereditary deafness is a major concern in white cats, and even more so if one or both irises are blue in color.

Researchers found that only 17 to 22 percent of white cats with non-blue eyes are born deaf. The percentage rises to 40 percent if the cat has one blue eye, while upwards of 65 to 85 percent of all-white cats with both eyes blue are /ask-elizabeth-white-cats-and-blindnessdeafness.

Hereditary deafness in a dog or cat is one of those rare cases when a veterinarian is sometimes able to make a diagnosis as he or she is walking through the exam room door. Dogs with the merle, piebald, or extreme white piebald genes are all at higher than average risk for being born with hearing deficits, as are cats with the “white” ://   White cats carrying the underlying cs Siamese dilution pigment gene can have blue eyes without deafness, and it has been suggested that the presence of this gene explains why purebred white cats are less often deaf than mixed-breed white cats (Pedersen, ).

Data supporting this is not available. From studies of mixed-breed white cats (the W   Hereditary Congenital Sensorineural Deafness usually linked to the genes responsible for white Dog – Recessive alleles of the piebald (s) gene: Irish spotting (si), piebald (sp), extreme-white piebald (sw) Dog – Dominant allele of the merle (M) gene Cat – Dominant allele of the white (W) gene deafness develops at weeks of age when the   6.

Delack JB. Hereditary deafness in the white cat. Compendium on Continuing Education for the Practicing Veterinarian 7.

Mair IWS. Hereditary deafness in the white cat. Acta Otolaryngologica Suppl 8. Mair IWS. Hereditary deafness in the Dalmatian dog.

Archives of Otorhinolaryngology 9. Strain GM ?pId=&id= 2 days ago  Canine hereditary deafness is associated with white pigment. This is controlled by the piebald locus on chromosome 20 and the merle locus on chromosome It /dog-breeding/exploring-genetics-canine-hereditary-deafness.

The incidence of inner ear degeneration varied from 20 % to 86 %, being dependent on the genetic composition of the population under consideration. The scope of further publications on hereditary deafness in the white cat is :// 1. Acta Otolaryngol Suppl. ; Hereditary deafness in the white cat.

Mair IW. PMID: [Indexed for MEDLINE] MeSH terms. Age Factors Hereditary deafness. This chapter highlights that inheritance is by far the most frequent cause of deafness in dogs and cats, but not all cases, wherein deafness is associated with the genes that cause white or lightened skin and hair.

The various causes of congenital deafness in dogs and cats Variability of the hereditary deafness in the white cat.

Physiology. Rebillard M, Rebillard G, Pujol R. Electrophysiological investigations, at different levels of the auditory pathway, were performed on 54 white cats. Hearing tests generally consisted of recording electrocochleograms or making audiograms from collicular or cortical ://   Of these, white cats have the highest risk of deafness.

According to International Cat Care: 5. The chance of deafness is as high as 80% in a white cat with 2 blue eyes.

But the odds drop for a white cat with just 1 blue eye, for whom there’s a 30–40% chance of deafness. For a white cat with no blue eyes, the chance of deafness falls to as The merle gene causes white pigment and has been associated with deafness in dogs.

The other gene is called piebald gene and it results in multi-colored patches of fur in the coat of the animal. This defect was noted as early as in dogs and in cats. These defects can cause deafness in other species like equine, bovine and :// Genetics of Congenital Deafness - Cat; domestic white cats have been studied the most absence of studies of pure breeds ; as in white gene-carrying dogs, inheritance does not follow inheritance of the gene itself in white cats ; white gene (W) - dominant homozygous cats do not appear to have additional health problems, except The temporal bones from 18 deaf Dalmatian dogs were examined with the light microscope, and the cochleo-saccular degeneration process studied.

End organ degeneration is already advanced by the age of 4 weeks, whilst loss of neurons in the spiral ganglion was found only in adult animals. Both processes are first evident in the central portion of the cochlea, and increase in extent with Deafness in pets is a very common problem and is increasingly being presented to veterinarians, as owners and breeders become more aware and concerned about such issues.

This book will provide complete coverage of the subject describing the anatomy and physiology of the auditory system, types of deafness, testing for deafness, methods of amelioration and management, behaviour of deaf animals In white cats out of two white parents, the combined prevalence was 52–96% across studies.

Combined deafness prevalence was 85% or 65% in cats with two blue eyes, 40% in cats with one blue eye, and 22% or 17% in cats with no blue eyes.

The deafness in white cats can Although deafness can be acquired throughout an animal’s life from a variety of causes, hereditary deafness, especially congenital hereditary deafness, is a significant problem in several species.

Extensive reviews exist of the genetics of deafness in humans and mice, but not for deafness in domestic animals. Hereditary deafness in many species and breeds is associated with loci for white Deafness can be hereditary or acquired, congenital or later onset, and sensorineural or conductive.

The most common cause of deafness in dogs and cats is congenital and hereditary, associated with white pigmentation. Adult and geriatric animals are most likely to be affected by otitis, drug toxicity, noise trauma, and :// white locus is associated with deafness in cats.

e genetics of coat color pigmentatio n in dogs and cats have been reviewed else- where (58 – 60); a partial listing is shown in Tab l e ://   WHITE CATS, EYE COLOURS AND DEAFNESS -Sarah Hartwell.

This page has two linked topics - the different causes of blue eyes and white fur in cats is one, the other is the relationship between eye colour, coat colour and   One of the most significant things that is associated with coat color in dogs is the fact that the color of your dog’s fur predicts the likelihood that your dog's hearing will be normal or :// Deafness in blue-eyed white cats is common and is known to be passed on as an autosomal dominant defect.

Blue eyes, resulting from an absence of pigment in the iris, is common with pigment-associated deafness but is not, in and of itself, an indication of deafness or the presence of a deafness gene; however, in several breeds dogs (Dalmatian Congenital sensorineural deafness has been reported frequently in experimental mixed-breed white cats but there is a paucity of data on occurrence of deafness in client-owned pure-breed white :// 2 days ago  Around the age of years some cats will start to show early signs of ageing such as blindess or changes can be a sign that there is a serious underlying medical problem (such as kidney disease or diabetes) but can also just be due to the cat getting :// This chapter highlights that inheritance is by far the most frequent cause of deafness in dogs and cats, but not all cases, wherein deafness is associated with the genes that cause white or lightened skin and hair.

The various causes of congenital deafness in dogs and cats are also ://   Free Online Library: The odds of deafness in white cats: the chances of a white cat being born deaf is 22 percent, but add blue eyes and it rises to 85 percent.(DEAF) by "Cat Watch"; Zoology and wildlife conservation Cats Statistics Deafness Domestic cats Genetic disorders+odds+of+deafness+in+white+cats:+the+chances+of+a.

Waardenburg's syndrome -- first described in by Dutch physician Petrus J. Waardenburg -- has several hallmarks, including widely spaced eyes that are pinched at the inner corners, deafness, light blue or mismatched eye color, fused eyebrows, and a white forelock of ://+gene;+sounding+out+the+heredity+of+deafness.Get this from a library!

Everyone here spoke sign language: hereditary deafness on Martha's Vineyard. [Nora Ellen Groce] -- Examines the reasons for the high rate of hereditary deafness among the population of Martha's Vineyard and discusses the place of deaf people in town ://  Congenital deafness in the domestic dog is usually related to the presence of white pigmentation, which is controlled primarily by the piebald locus on chromosome 20 and also by merle on chromosome Pigment-associated deafness is also seen in other species, including cats, mice, sheep, alpacas, horses, cows, pigs, and humans, but the genetic factors determining why some piebald or ?id=/